The addition of glucose to cells of the yeast Saccharomyces cerevisiae triggers a variety of regulatory phenomena. Initial glucose metabolism is required for the induction of most of them. Mutants deficient in both glucose-induced signalling and the control of initial glucose metabolism have a defect in the trehalose-6-phosphate synthase catalytic subunit of the trehalose synthase complex. This finding has raised novel questions about the control of glucose influx into glycolysis in yeast and its connection to the glucose-sensing mechanism. This dual function of the trehalose-6-phosphate synthase subunit has been found in several yeast species, suggesting that this control system might be widespread in fungi and possibly also in other organisms.
|Evidence ID||Analyze ID||Interactor||Interactor Systematic Name||Interactor||Interactor Systematic Name||Type||Assay||Annotation||Action||Modification||Phenotype||Source||Reference||Note|
|Evidence ID||Analyze ID||Gene||Gene Systematic Name||Gene Ontology Term||Gene Ontology Term ID||Qualifier||Aspect||Method||Evidence||Source||Assigned On||Reference||Annotation Extension|
|Evidence ID||Analyze ID||Gene||Gene Systematic Name||Phenotype||Experiment Type||Experiment Type Category||Mutant Information||Strain Background||Chemical||Details||Reference|
|Evidence ID||Analyze ID||Regulator||Regulator Systematic Name||Target||Target Systematic Name||Experiment||Conditions||Strain||Source||Reference|