Reference: Weng Y, et al. (2011) Ganodermasides C and D, two new anti-aging ergosterols from spores of the medicinal mushroom Ganoderma lucidum. Biosci Biotechnol Biochem 75(4):800-3

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Abstract


Two new anti-aging compounds, ganodermasides C and D, were isolated and their structures elucidated. They are novel ergosterols possessing a 4,6,8(14),22-tetraene-3-one unit with unique hydroxylation at C-9. Both of them significantly extended the replicative lifespan of the K6001 yeast strain. Ganodermasides C and D regulated the expression of the gene for UTH1 to prolong the replicative lifespan of yeast.

Reference Type
Journal Article
Authors
Weng Y, Lu J, Xiang L, Matsuura A, Zhang Y, Huang Q, Qi J
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