Reference: Giorgi C and Moore MJ (2007) The nuclear nurture and cytoplasmic nature of localized mRNPs. Semin Cell Dev Biol 18(2):186-93

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Abstract

From yeast to mammals, evidence has emerged in recent years highlighting the essential role played by the nuclear "history" of a messenger RNA in determining its cytoplasmic fate. mRNA localization, translation and stability in the cytoplasm are often pre-destined in the nucleus, and directed by the composition and architecture of nuclear assembled mRNA-protein complexes. In this review we focus on nuclear-acquired RNA-binding proteins and complexes that participate in determining the journey of localized mRNAs.

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Journal Article
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Giorgi C, Moore MJ
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