Reference: Stemmann O, et al. (2005) Rephrasing anaphase: separase FEARs shugoshin. Chromosoma 113(8):409-17

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Abstract


Cleavage of the ring-like cohesin complex by separase triggers segregation of sister chromatids in anaphase. This simplistic model has recently been extended by exciting discoveries on three levels: regulation of anaphase by posttranslational modifications and the cohesin protector shugoshin; non-proteolytic roles of separase; and cohesin-independent linkage of sister chromatids.

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Journal Article | Review | Research Support, Non-U.S. Gov't
Authors
Stemmann O, Boos D, Gorr IH
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