Reference: Chua G, et al. (2004) Transcriptional networks: reverse-engineering gene regulation on a global scale. Curr Opin Microbiol 7(6):638-46

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Abstract


A major objective in post-genome research is to fully understand the transcriptional control of each gene and the targets of each transcription factor. In yeast, large-scale experimental and computational approaches have been applied to identify co-regulated genes, cis regulatory elements, and transcription factor DNA binding sites in vivo. Methods for modeling and predicting system behavior, and for reconciling discrepancies among data types, are being explored. The results indicate that a complete and comprehensive yeast transcriptional network will ultimately be achieved.

Reference Type
Journal Article | Review | Research Support, Non-U.S. Gov't
Authors
Chua G, Robinson MD, Morris Q, Hughes TR
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Interaction Annotations


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Interactor Interactor Type Assay Annotation Action Modification Phenotype Source Reference

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Gene Gene Ontology Term Qualifier Aspect Method Evidence Source Assigned On Annotation Extension Reference

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Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

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