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Reference: Jacobson A (2004) Regulation of mRNA decay: decapping goes solo. Mol Cell 15(1):1-2

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Abstract

In this issue of Molecular Cell, Badis et al. demonstrate that autoregulated destabilization of the RPS28B mRNA is mediated by Edc3p interaction with an Rps28p/3'UTR mRNP complex. Subsequent recruitment of Dcp1p/Dcp2p to the complex appears to ensure rapid, deadenylation-independent decapping of the mRNA.

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Comment | Journal Article | Review
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Jacobson A
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