Reference: Bickford LC, et al. (2004) A structural view of the COPII vesicle coat. Curr Opin Struct Biol 14(2):147-53

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Abstract

The COPII vesicle coat coordinates the budding of transport vesicles from the endoplasmic reticulum in the initial step of the secretory pathway. The coat orchestrates a sequence of events including self-assembly on the membrane, cargo and SNARE molecule selection, and deformation of the membrane into a bud to drive vesicle fission. Recent molecular-level studies have helped to explain how the three components of yeast COPII - Sar1 GTPase, the Sec23/24 subcomplex and the Sec13/31 subcomplex - combine to organize this complex process.

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Journal Article | Review | Review, Tutorial
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Bickford LC, Mossessova E, Goldberg J
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