Reference: Morgan DO (1999) Regulation of the APC and the exit from mitosis. Nat Cell Biol 1(2):E47-53

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Abstract

The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.

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Journal Article | Review | Research Support, U.S. Gov't, P.H.S.
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Morgan DO
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