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Morgan DO  (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13():261-91

Abstract: Cyclin-dependent kinases (Cdks) play a well-established role in the regulation of the eukaryotic cell division cycle and have also been implicated in the control of gene transcription and other processes. Cdk activity is governed by a complex network of regulatory subunits and phosphorylation events whose precise effects on Cdk conformation have been revealed by recent crystallographic studies. In the cell, these regulatory mechanisms generate an interlinked series of Cdk oscillators that trigger the events of cell division.

Status: Published Type: Journal Article | Review | Review, Academic PubMed ID: 9442875

Topics addressed in this paper

Number of different genes curated to this paper: 14

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Topics Genes linked to topics (#1 - 10 )
CDC28 CKS1 CLB1 CLB2 CLB3 CLB4 CLB5 CLB6 CLN1 CLN2
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Topics Genes linked to topics (#11 - 14 )
CLN3 MIH1 SIC1 SWE1
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