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Will CL and Luhrmann R (1997) Protein functions in pre-mRNA splicing. Curr Opin Cell Biol 9(3):320-8
Abstract: Proteins have been implicated in an expanding variety of functions during pre-mRNA splicing. Molecular cloning has identified genes encoding spliceosomal proteins that potentially act as novel RNA helicases, GTPases, or protein isomerases. Novel protein-protein and protein-RNA interactions that are required for functional spliceosome formation have also been described. Finally, growing evidence suggests that proteins may contribute directly to the spliceosome's active sites.
| Status: Published | Type: Journal Article | Review | Review, Academic | PubMed ID: 9159080 |
Topics addressed in this paper
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