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Decottignies A and Goffeau A  (1997) Complete inventory of the yeast ABC proteins. Nat Genet 15(2):137-45

Abstract: The complete sequence of the yeast genome predicts the existence of 29 proteins belonging to the ubiquitous ATP-binding cassette (ABC) superfamily. Using binary comparison, phylogenetic classification and detection of conserved amino acid residues, the yeast ABC proteins have been classified in a total of six clusters, including ten subclusters of distinct predicted topology and presumed distinct function. Study of the yeast ABC proteins provides insight into the physiological function and biochemical mechanisms of their human homologues, such as those involved in cystic fibrosis, adrenoleukodystrophy, Zellweger syndrome, multidrug resistance and the antiviral activity of interferons.

Status: Published Type: Journal Article PubMed ID: 9020838

Topics addressed in this paper

Number of different genes curated to this paper: 30

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Topics Genes linked to topics (#1 - 10 )
ADP1 ARB1 ATM1 AUS1 BPT1 CAF16 GCN20 HEF3 MDL1 MDL2
Disease Gene Related blue ball
Fungal Related Genes/Proteins blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Non-Fungal Related Genes/Proteins blue ball
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Topics Genes linked to topics (#11 - 20 )
NEW1 NFT1 PDR10 PDR11 PDR12 PDR15 PDR18 PDR5 PXA1 PXA2
Disease Gene Related blue ball
Fungal Related Genes/Proteins blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball
Protein Sequence Features blue ball
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Topics Genes linked to topics (#21 - 30 )
RLI1 SNQ2 STE6 VMR1 YBT1 YCF1 YEF3 YKR104W YOL075C YOR1
Additional Literature blue ball
Fungal Related Genes/Proteins blue ball blue ball blue ball blue ball blue ball blue ball
Other Features blue ball blue ball
Reviews blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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