Schirmer EC, et al. (1996) HSP100/Clp proteins: a common mechanism explains diverse functions. Trends Biochem Sci 21(8):289-96
Abstract: The HSP100/Clp proteins are a newly discovered family with a great diversity of functions, such as increased tolerance to high temperatures, promotion of proteolysis of specific cellular substrates and regulation of transcription. HSP100/Clp proteins are also synthesized in a variety of specific patterns and, in eukaryotes, are localized to different subcellular compartments. Recent data suggest that a common ability to disassemble higher-order protein structures and aggregates unifies the molecular functions of this diverse family.
|Status: Published||Type: Journal Article | Review | Review, Tutorial||PubMed ID: 8772382|
Topics addressed in this paper
- To go to the Locus page for a gene, click on the gene name.