Peterson CL and Tamkun JW (1995) The SWI-SNF complex: a chromatin remodeling machine? Trends Biochem Sci 20(4):143-6
Abstract: The SWI-SNF complex plays a key role in the regulation of eukaryotic gene expression. Genetic studies in the yeast Saccharomyces cerevisiae suggest that one role for the complex is to antagonize chromatin-mediated repression of transcription. Recent biochemical studies indicate that S. cerevisiae and putative human SWI-SNF complexes use the energy of ATP hydrolysis to disrupt nucleosome structure.
|Status: Published||Type: Journal Article | Review | Review, Tutorial||PubMed ID: 7770913|
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