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Smith MR, et al. (2013) Identification of gold nanoparticle-resistant mutants of Saccharomyces cerevisiae suggests a role for respiratory metabolism in mediating toxicity. Appl Environ Microbiol 79(2):728-33
Abstract: Positively charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 ?g/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion.
| Status: Published | Type: Journal Article | PubMed ID: 23144132 |
Topics addressed in this paper
Number of different genes curated to this paper: 17
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ABF2 | BOI2 | CCM1 | CIR1 | CUP2 | DDR48 | GYL1 | IMG1 | MRPL37 | MRPL4 | |
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| Topics | Genes linked to topics (#11 - 17 ) | ||||||
|---|---|---|---|---|---|---|---|
| MRPL51 | NAM2 | RTC6 | STP2 | TRK1 | UBP8 | YMR155W | |
| Primary Literature | | | | | | | |
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