SGD Paper Help


Page Contents:
Aulds J, et al.  (2012) Global identification of new substrates for the yeast endoribonuclease, RNase mitochondrial RNA processing (MRP). J Biol Chem 287(44):37089-97

Abstract: RNase mitochondrial RNA processing (MRP) is an essential, evolutionarily conserved endoribonuclease composed of 10 different protein subunits and a single RNA. RNase MRP has established roles in multiple pathways including ribosome biogenesis, cell cycle regulation, and mitochondrial DNA replication. Although each of these functions is important to cell growth, additional functions may exist given the essential nature of the complex. To identify novel RNase MRP substrates, we utilized RNA immunoprecipitation and microarray chip analysis to identify RNA that physically associates with RNase MRP. We identified several new potential substrates for RNase MRP including a cell cycle-regulated transcript, CTS1; the yeast homolog of the mammalian p27(Kip1), SIC1; and the U2 RNA component of the spliceosome. In addition, we found RNase MRP to be involved in the regulation of the Ty1 transposon RNA. These results reinforce and broaden the role of RNase MRP in cell cycle regulation and help to identify new roles of this endoribonuclease.

Status: Published Type: Journal Article PubMed ID: 22977255

Topics addressed in this paper

Number of different genes curated to this paper: 55

Jump to Summary Chart for:
  • To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  • displays other papers with information about that topic for that gene.
  • displays other papers in SGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
  • To go to the Locus page for a gene, click on the gene name.
Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
CTS1 DBR1 HTB1 LEA1 LSR1 MSL1 NME1 NOP1 POP1 POP3
Additional Literature blue ball blue ball
Genetic Interactions blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Protein-Nucleic Acid Interactions blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball
Strains/Constructs blue ball
Substrates/Ligands/Cofactors blue ball blue ball blue ball
Techniques and Reagents yg ball
Transcription blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#11 - 20 )
POP4 POP5 POP6 POP7 POP8 PUS7 RMP1 RPL31B RPL34A RPP1
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball
Genetic Interactions blue ball
Mutants/Phenotypes blue ball blue ball
Primary Literature blue ball blue ball blue ball blue ball
Protein-Nucleic Acid Interactions blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Regulation of blue ball blue ball
RNA Levels and Processing blue ball blue ball
Strains/Constructs blue ball
Substrates/Ligands/Cofactors blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Transcription blue ball blue ball

Topics Genes linked to topics (#21 - 30 )
SIC1 SNM1 STM1 XRN1 YARCTy1-1 YBLWTy1-1 YBRWTy1-2 YDRCTy1-1 YDRCTy1-2 YDRCTy1-3
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball
Genetic Interactions blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball
Non-Fungal Related Genes/Proteins blue ball
Primary Literature blue ball blue ball blue ball blue ball
Protein-Nucleic Acid Interactions blue ball blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Strains/Constructs blue ball
Substrates/Ligands/Cofactors blue ball
Transcription blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Jump to Summary Chart for:
  • To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  • displays other papers with information about that topic for that gene.
  • displays other papers in SGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
  • To go to the Locus page for a gene, click on the gene name.

Topics Genes linked to topics (#31 - 40 )
YDRWTy1-4 YDRWTy1-5 YERCTy1-1 YERCTy1-2 YGRCTy1-2 YGRCTy1-3 YGRWTy1-1 YHRCTy1-1 YJRWTy1-1 YJRWTy1-2
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Transcription blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#41 - 50 )
YLRCTy1-1 YLRWTy1-2 YLRWTy1-3 YMLWTy1-1 YMLWTy1-2 YMRCTy1-3 YMRCTy1-4 YNLCTy1-1 YNLWTy1-2 YOLWTy1-1
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Transcription blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#51 - 55 )
YORWTy1-2 YPLWTy1-1 YPRCTy1-2 YPRCTy1-4 YPRWTy1-3
Additional Literature blue ball blue ball blue ball blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball
Transcription blue ball blue ball blue ball blue ball blue ball
Jump to Summary Chart for:
  • To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  • displays other papers with information about that topic for that gene.
  • displays other papers in SGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
  • To go to the Locus page for a gene, click on the gene name.

Author Searches

To find contact information or other publications by the authors of this paper, follow these three steps:
  1. (1) Choose an author,
  2. (2) Choose a search parameter,
  3. (3) Click to implement
Page Contents: