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Parker R  (2012) RNA Degradation in Saccharomyces cerevisae. Genetics 191(3):671-702

Abstract: All RNA species in yeast cells are subject to turnover. Work over the past 20 years has defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs, and noncoding RNAs. In addition, numerous quality control mechanisms that target aberrant RNAs have been identified. Generally, each decay mechanism contains factors that funnel RNA substrates to abundant exo- and/or endonucleases. Key issues for future work include determining the mechanisms that control the specificity of RNA degradation and how RNA degradation processes interact with translation, RNA transport, and other cellular processes.

Status: Published Type: Journal Article PubMed ID: 22785621

Topics addressed in this paper

Number of different genes curated to this paper: 92

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Topics Genes linked to topics (#1 - 10 )
AIR1 AIR2 BTT1 CAF120 CAF130 CAF16 CAF4 CAF40 CDC36 CDC39
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Topics Genes linked to topics (#11 - 20 )
CSL4 CTH1 DCP1 DCP2 DCS1 DHH1 DOM34 DSS1 EDC1 EDC2
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Topics Genes linked to topics (#21 - 30 )
EDC3 HBS1 HYP2 LRP1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6
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Topics Genes linked to topics (#31 - 40 )
LSM7 LSR1 MFA2 MMS1 MOT2 MPP6 MPT5 MRT4 MTR3 NAB3
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Topics Genes linked to topics (#41 - 50 )
NAM7 NMD2 NOT3 NOT5 NRD1 NUC1 PAB1 PAN2 PAN3 PAP2
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Topics Genes linked to topics (#51 - 60 )
PAT1 PET127 PKH1 PKH2 POP2 RAI1 RAT1 REX2 RNY1 RPB4
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Topics Genes linked to topics (#61 - 70 )
RPB7 RPL10 RRP4 RRP40 RRP42 RRP43 RRP45 RRP46 RRP6 RRP7
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Topics Genes linked to topics (#71 - 80 )
RTT101 SBP1 SCD6 SKI2 SKI3 SKI6 SKI7 SKI8 SLA2 SNR19
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Topics Genes linked to topics (#81 - 90 )
SNR7-L SNR7-S STM1 SUP35 SUV3 THS1 TIS11 TLC1 TPA1 TRF5
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Topics Genes linked to topics (#91 - 92 )
UPF3 XRN1
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