Timmer S, et al. (2012) The journey of resveratrol from yeast to human. Aging (Albany NY) 4(3):146-58
Abstract: The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.
|Status: Published||Type: Journal Article | Review||PubMed ID: 22436213|
Topics addressed in this paper
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