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Luo X and Yu H  (2012) Mitosis: short-circuiting spindle checkpoint signaling. Curr Biol 22(4):R128-30

Abstract: The spindle checkpoint forms an intricate signaling circuit to sense unattached kinetochores, to inhibit the anaphase-promoting complex/cyclosome (APC/C), and to delay anaphase onset. Using clever genetic experiments in the budding yeast, Lau and Murray define the endpoint of checkpoint signaling and provide key mechanistic insights into checkpoint inhibition of APC/C.CI - Copyright A(c) 2012 Elsevier Ltd. All rights reserved.

Status: Published Type: Journal Article PubMed ID: 22361149

Topics addressed in this paper

Number of different genes curated to this paper: 25

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Topics Genes linked to topics (#1 - 10 )
AMA1 APC1 APC11 APC2 APC4 APC5 APC9 BUB1 BUB3 CBF2
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Topics Genes linked to topics (#11 - 20 )
CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 DOC1 IPL1 MAD1 MAD2
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Topics Genes linked to topics (#21 - 25 )
MAD3 MND2 MPS1 PDS1 SWM1
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