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Tutucci E and Stutz F  (2011) Keeping mRNPs in check during assembly and nuclear export. Nat Rev Mol Cell Biol 12(6):377-84

Abstract: The cell nucleus is an intricate organelle that coordinates multiple activities that are associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic information and the machineries that control the production of mature and export-competent messenger ribonucleoproteins (mRNPs), a multistep process that is regulated in a spatial and temporal manner. Recent studies suggest that post-translational modifications play a part in coordinating the co-transcriptional assembly, remodelling and export of mRNP complexes through nuclear pores, adding a new level of regulation to the process of gene expression.

Status: Published Type: Journal Article PubMed ID: 21602906

Topics addressed in this paper

Number of different genes curated to this paper: 84

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Topics Genes linked to topics (#1 - 10 )
ABD1 ADA2 AIR1 AIR2 ASH1 CDC28 CDC31 CDC33 CEG1 CET1
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Topics Genes linked to topics (#11 - 20 )
CHD1 DBP5 DIS3 ESC1 GAL1 GAL10 GAL2 GAL3 GAL4 GAL7
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Topics Genes linked to topics (#21 - 30 )
GCN5 GLC7 GLE1 HFI1 HMT1 HPR1 HRP1 HSP104 HXK1 INO1
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Topics Genes linked to topics (#31 - 40 )
IPK1 LAP3 MEX67 MFT1 MLP1 MLP2 MTR2 MTR4 NAB2 NGG1
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Topics Genes linked to topics (#41 - 50 )
NPL3 NRD1 NUP1 NUP159 NUP60 PAP1 PAP2 PCF11 PGM2 PML39
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Topics Genes linked to topics (#51 - 60 )
RAI1 RAT1 RPO21 RRP6 RSP5 SAC3 SGF11 SGF29 SGF73 SKY1
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Topics Genes linked to topics (#61 - 70 )
SLT2 SPT20 SPT3 SPT7 SPT8 SUB2 SUS1 SWT1 TAF10 TAF12
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Topics Genes linked to topics (#71 - 80 )
TAF5 TAF6 TAF9 TEX1 THO2 THP1 THP2 TOM1 TRA1 TRF5
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Topics Genes linked to topics (#81 - 84 )
UBI4 UBP8 ULP1 YRA1
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