Halfmann R and Lindquist S (2010) Epigenetics in the extreme: prions and the inheritance of environmentally acquired traits. Science 330(6004):629-32
Abstract: Prions are an unusual form of epigenetics: Their stable inheritance and complex phenotypes come about through protein folding rather than nucleic acid-associated changes. With intimate ties to protein homeostasis and a remarkable sensitivity to stress, prions are a robust mechanism that links environmental extremes with the acquisition and inheritance of new traits.
|Status: Published||Type: Journal Article | Research Support, Non-U.S. Gov't||PubMed ID: 21030648|
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