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Solieri L  (2010) Mitochondrial inheritance in budding yeasts: towards an integrated understanding. Trends Microbiol 18(11):521-30

Abstract: Recent advances in yeast mitogenomics have significantly contributed to our understanding of the diversity of organization, structure and topology in the mitochondrial genome of budding yeasts. In parallel, new insights on mitochondrial DNA (mtDNA) inheritance in the model organism Saccharomyces cerevisiae highlighted an integrated scenario where recombination, replication and segregation of mtDNA are intricately linked to mitochondrial nucleoid (mt-nucleoid) structure and organelle sorting. In addition to this, recent discoveries of bifunctional roles of some mitochondrial proteins have interesting implications on mito-nuclear genome interactions and the relationship between mtDNA inheritance, yeast fitness and speciation. This review summarizes the current knowledge on yeast mitogenomics, mtDNA inheritance with regard to mt-nucleoid structure and organelle dynamics, and mito-nuclear genome interactions.CI - Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Status: Published Type: Journal Article PubMed ID: 20832322

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Number of different genes curated to this paper: 13

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ABF2 ATP6 ATP8 CCE1 COB COX1 COX2 COX3 HSP60 MHR1
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Topics Genes linked to topics (#11 - 13 )
NTG1 RPO41 VAR1
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