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Spang A, et al. (2010) Arf GAPs: gatekeepers of vesicle generation. FEBS Lett 584(12):2646-51
Abstract: Arf GAP proteins are a versatile and diverse group of proteins. They control the activity of the GTP-binding proteins of the ARF family by inducing the hydrolysis of GTP that is bound to Arf proteins. The best-studied role of Arf GAPs is in intracellular traffic. In this review, we will focus mainly on the Arf GAPs that play a role in vesicle formation, ARFGAP1, ARFGAP2 and ARFGAP3 and their yeast homologues, Gcs1p and Glo3p. We discuss the roles of Arf GAPs as regulators and effectors for Arf GTP-binding proteins.CI - Copyright (c) 2010 Federation of European Biochemical Societies. All rights reserved.
| Status: Published | Type: Journal Article | PubMed ID: 20394747 |
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