Elston TC (2008) Probing pathways periodically. Sci Signal 1(42):pe47
Abstract: Signal transduction pathways are used by cells to process and transmit information about their external surroundings. These systems are dynamic, interconnected molecular networks. Therefore, full characterization of their behavior requires a systems-level analysis. Investigations with temporally oscillating input signals probed the dynamic properties of the high-osmolarity glycerol (HOG) pathway of the budding yeast Saccharomyces cerevisiae. These studies shed light on how the network functions as a whole to respond to changing environmental conditions.
|Status: Published||Type: Journal Article||PubMed ID: 18941138|
Topics addressed in this paper
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