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Gardner MK and Odde DJ (2008) Dam1 complexes go it alone on disassembling microtubules. Nat Cell Biol 10(4):379-81
Abstract: Kinetochores maintain a mechanical grip on disassembling microtubule plus ends, possibly through a 16-member Dam1 ring that acts as a sliding clamp. It turns out, however, that a ring is not required for maintaining grip: individual Dam1 complexes in vitro can diffuse on the microtubule lattice and track shortening microtubule tips.
| Status: Published | Type: Comment | Journal Article | PubMed ID: 18379597 |
Topics addressed in this paper
Number of different genes curated to this paper: 10
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