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Weake VM and Workman JL  (2008) Histone ubiquitination: triggering gene activity. Mol Cell 29(6):653-63

Abstract: Recently, many of the enzymes responsible for the addition and removal of ubiquitin from the histones H2A and H2B have been identified and characterized. From these studies, it has become clear that H2A and H2B ubiquitination play critical roles in regulating many processes within the nucleus, including transcription initiation and elongation, silencing, and DNA repair. In this review, we present the enzymes involved in H2A and H2B ubiquitination and discuss new evidence that links histone ubiquitination to other chromatin modifications, which has provided a model for the role of H2B ubiquitination, in particular, in transcription initiation and elongation.

Status: Published Type: Journal Article | Review PubMed ID: 18374642

Topics addressed in this paper

Number of different genes curated to this paper: 33

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Topics Genes linked to topics (#1 - 10 )
BRE1 BUR2 CAF130 CAF40 CCR4 CDC36 CDC39 CDC73 CTK1 CTR9
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Topics Genes linked to topics (#11 - 20 )
DOT1 HTB1 HTB2 HTZ1 KIN28 LEO1 LGE1 MOT2 NOT3 NOT5
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Topics Genes linked to topics (#21 - 30 )
PAF1 POP2 RAD6 RPT4 RPT6 RTF1 SET1 SGF11 SGV1 SUS1
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Jump to Summary Chart for:
  • To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  • displays other papers with information about that topic for that gene.
  • displays other papers in SGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
  • To go to the Locus page for a gene, click on the gene name.

Topics Genes linked to topics (#31 - 33 )
SWD2 UBP10 UBP8
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