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Kaeberlein M, et al.  (2007) Recent developments in yeast aging. PLoS Genet 3(5):e84

Abstract: In the last decade, research into the molecular determinants of aging has progressed rapidly and much of this progress can be attributed to studies in invertebrate eukaryotic model organisms. Of these, single-celled yeast is the least complicated and most amenable to genetic and molecular manipulations. Supporting the use of this organism for aging research, increasing evidence has accumulated that a subset of pathways influencing longevity in yeast are conserved in other eukaryotes, including mammals. Here we briefly outline aging in yeast and describe recent findings that continue to keep this "simple" eukaryote at the forefront of aging research.

Status: Published Type: Journal Article | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't PubMed ID: 17530929

Topics addressed in this paper

Number of different genes curated to this paper: 17

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Topics Genes linked to topics (#1 - 10 )
CYR1 FOB1 HAP4 IDH2 MCA1 MSN2 MSN4 RAS1 RAS2 RPL10
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Topics Genes linked to topics (#11 - 17 )
RPS6B RTG1 RTG3 SCH9 SIR2 TOR1 TOR2
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