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Bruno I and Wilkinson MF (2006) P-bodies react to stress and nonsense. Cell 125(6):1036-8
Abstract: P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
| Status: Published | Type: Comment | Journal Article | PubMed ID: 16777595 |
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