Kolas NK and Durocher D (2006) DNA repair: DNA polymerase zeta and Rev1 break in. Curr Biol 16(8):R296-9
Abstract: DNA polymerase zeta and Rev1 play key roles in replication past DNA lesions. New work shows that the yeast checkpoint kinase Mec1 recruits a complex consisting of polymerase zeta and Rev1 to DNA double-strand breaks. This study highlights the role of polymerases that mediate translesion synthesis in the response to DNA double-strand breaks.
|Status: Published||Type: Journal Article||PubMed ID: 16631579|
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