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de Lichtenberg U, et al.  (2005) New weakly expressed cell cycle-regulated genes in yeast. Yeast 22(15):1191-201

Abstract: We present an approach combining bioinformatics prediction with experimental microarray validation to identify new cell cycle-regulated genes in Saccharomyces cerevisiae. We identify in the order of 100 new cell cycle-regulated genes and show by independent data that these genes in general tend to be more weakly expressed than the genes identified hitherto. Among the genes not previously suggested to be periodically expressed we find genes linked to DNA repair, cell size monitoring and transcriptional control, as well as a number of genes of unknown function. Several of the gene products are believed to be phosphorylated by Cdc28. For many of these new genes, homologues exist in Schizosaccharomyces pombe and Homo sapiens for which the expression also varies with cell cycle progression. Copyright (c) 2005 John Wiley & Sons, Ltd.

Status: Published Type: Journal Article PubMed ID: 16278933

Topics addressed in this paper

Number of different genes curated to this paper: 71

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Topics Genes linked to topics (#1 - 10 )
ACE2 ACM1 ADD37 AIM34 ALY2 ATG36 CLB3 CLB4 COS9 CSI2
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#11 - 20 )
DIF1 DSE3 FKH1 GAS3 GRX6 HCM1 HIF1 HXT1 INP2 IRC8
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#21 - 30 )
LDB19 MEC3 MLH2 MMR1 MPS1 MSA2 MUS81 NBP1 NDD1 PAN3
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#31 - 40 )
PDR15 PHO12 POG1 REB1 RKM1 RME1 ROM2 RSF2 SAK1 SCW11
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Alias blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#41 - 50 )
SRF1 SRS2 SWI4 SWI5 SWI6 TDA7 TIR4 TOS2 TOS4 VHR1
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#51 - 60 )
WHI3 WHI4 YAP5 YBR071W YEN1 YIR016W YJL160C YJL181W YJL206C YJR098C
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#61 - 70 )
YLR326W YLR455W YML083C YML119W YNL058C YNR014W YOR019W YOR378W YOX1 YPL168W
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#71 )
YPR015C
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