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Bjorklund S and Gustafsson CM  (2005) The yeast Mediator complex and its regulation. Trends Biochem Sci 30(5):240-4

Abstract: The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.

Status: Published Type: Journal Article PubMed ID: 15896741

Topics addressed in this paper

Number of different genes curated to this paper: 24

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Topics Genes linked to topics (#1 - 10 )
CSE2 GAL11 MED1 MED11 MED2 MED4 MED6 MED7 MED8 NUT2
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Topics Genes linked to topics (#11 - 20 )
PGD1 RGR1 ROX3 SIN4 SRB2 SRB4 SRB5 SRB6 SRB7 SRB8
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Topics Genes linked to topics (#21 - 24 )
SSN2 SSN3 SSN8 TAF14
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