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Galgoczy DJ, et al.  (2004) Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(52):18069-74

Abstract: The budding yeast Saccharomyces cerevisiae has three cell types (a cells, alpha cells, and a/alpha cells), each of which is specified by a unique combination of transcriptional regulators. This transcriptional circuit has served as an important model for understanding basic features of the combinatorial control of transcription and the specification of cell type. Here, using genome-wide chromatin immunoprecipitation, transcriptional profiling, and phylogenetic comparisons, we describe the complete cell-type-specification circuit for S. cerevisiae. We believe this work represents a complete description of cell-type specification in a eukaryote.

Status: Published Type: Journal Article PubMed ID: 15604142

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Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
AGA2 AMN1 AXL1 BAR1 CCW12 DDR2 FAR1 FUS3 GPA1 HO
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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HOG1 ICS2 MATA1 MATALPHA1 MATALPHA2 MCM1 MF(ALPHA)1 MF(ALPHA)2 MFA1 MFA2
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Topics Genes linked to topics (#21 - 30 )
NEJ1 RDH54 SAG1 STE18 STE2 STE3 STE4 STE5 STE6 YLR040C
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Topics Genes linked to topics (#31 )
YLR041W
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