SGD Paper 
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Ahner A and Brodsky JL (2004) Checkpoints in ER-associated degradation: excuse me, which way to the proteasome? Trends Cell Biol 14(9):474-8
Abstract: The failure of secreted proteins to fold results in their retrotranslocation from the endoplasmic reticulum (ER) and degradation by the proteasome in a process called "ER-associated degradation" (ERAD). Two recent studies indicate that ERAD substrates are targeted to different pathways depending on the topology of the substrate and the subcellular location of the misfolded domain.
| Status: Published | Type: Journal Article | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S. | Review | PubMed ID: 15350974 |
Topics addressed in this paper
Number of different genes curated to this paper: 18
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CDC48 | CWC23 | DER1 | HLJ1 | HRD1 | HRD3 | HSP104 | JEM1 | JID1 | KAR2 | |
| Reviews |  | | | | | | | | | |
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