Longtine MS and Bi E (2003) Regulation of septin organization and function in yeast. Trends Cell Biol 13(8):403-9
Abstract: Septins are a conserved eukaryotic family of GTP-binding filament-forming proteins with functions in cytokinesis and other processes. In the budding yeast Saccharomyces cerevisiae, septins initially localize to the presumptive bud site and then to the cortex of the mother-bud neck as an hourglass structure. During cytokinesis, the septin hourglass splits and single septin rings partition with each of the resulting cells. Septins are thought to function in diverse processes in S. cerevisiae, mainly by acting as a scaffold to direct the neck localization of septin-associated proteins.
|Status: Published||Type: Journal Article | Review | Review, Tutorial||PubMed ID: 12888292|
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