Stenmark H, et al. (2002) The phosphatidylinositol 3-phosphate-binding FYVE finger. FEBS Lett 513(1):77-84
Abstract: The FYVE zinc finger domain is conserved from yeast (five proteins) to man (27 proteins). It functions in the membrane recruitment of cytosolic proteins by binding to phosphatidylinositol 3-phosphate (PI3P), which is found mainly on endosomes. Here we review recent work that sheds light on the targeting of FYVE finger proteins to PI3P-containing membranes, and how these proteins serve to regulate multiple cellular functions.
|Status: Published||Type: Journal Article | Research Support, Non-U.S. Gov't||PubMed ID: 11911884|
Topics addressed in this paper
Number of different genes curated to this paper: 6
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