SGD Paper 
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Wassmann K and Benezra R (2001) Mitotic checkpoints: from yeast to cancer. Curr Opin Genet Dev 11(1):83-90
Abstract: Separation of chromosomes during mitosis is monitored by a checkpoint that leads to cell-cycle arrest if the chromosomes are not properly attached to the mitotic spindle. Molecular mechanisms controlling this checkpoint have been identified. In addition, loss of this checkpoint has been shown to result in chromosome missegregation in higher eukaryotes and may contribute to the genomic instability observed in human cancers.
| Status: Published | Type: Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S. | Review | PubMed ID: 11163156 |
Topics addressed in this paper
Number of different genes curated to this paper: 16
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| BUB1 | BUB2 | BUB3 | CDC14 | CDC20 | CDC28 | CDH1 | CLB2 | CLB5 | ESP1 | |
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