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Kortschak RD, et al. (2000) ARID proteins come in from the desert. Trends Biochem Sci 25(6):294-9
Abstract: Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure.
| Status: Published | Type: Journal Article | Review | PubMed ID: 10838570 |
Topics addressed in this paper
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