Komeili A and O'Shea EK (2000) Nuclear transport and transcription. Curr Opin Cell Biol 12(3):355-60
Abstract: The compartmentalization of DNA in the nucleus of eukaryotic cells establishes a connection between the nuclear transport machinery and the transcriptional apparatus. General transcription factors, as well as specific transcriptional activators and repressors, such as p53 and NF-AT, need to be imported into the nucleus following their translation. In addition, nuclear transport plays a crucial role in regulating the activity of many transcription factors.
|Status: Published||Type: Journal Article | Review | Review, Tutorial||PubMed ID: 10801461|
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