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Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8

Abstract: The hexose transporter family of Saccharomyces cerevisiae comprises 18 proteins (Hxt1-17, Gal2). Here, we demonstrate that all these proteins, except Hxt12, and additionally three members of the maltose transporter family (Agt1, Ydl247, Yjr160) are able to transport hexoses. In a yeast strain deleted for HXT1-17, GAL2, AGT1, YDL247w and YJR160c, glucose consumption and transport activity were completely abolished. However, as additional deletion of the glucose sensor gene SNF3 partially restored growth on hexoses, our data indicate the existence of even more proteins able to transport hexoses in yeast.

Status: Published Type: Journal Article PubMed ID: 10618490

Topics addressed in this paper

Number of different genes curated to this paper: 28

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Topics Genes linked to topics (#1 - 10 )
GAL2 GIT1 HXT1 HXT10 HXT11 HXT12 HXT13 HXT14 HXT15 HXT16
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Topics Genes linked to topics (#11 - 20 )
HXT17 HXT2 HXT3 HXT4 HXT5 HXT6 HXT7 HXT8 HXT9 ITR1
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Topics Genes linked to topics (#21 - 28 )
MAL11 MPH2 MPH3 RGT2 SNF3 STL1 YDR387C YIL171W
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