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Winzeler EA, et al.  (1999) Whole genome genetic-typing in yeast using high-density oligonucleotide arrays. Parasitology 118 Suppl:S73-80

Abstract: Genome sequence information in combination with new technologies has allowed researchers to approach genetic problems in new ways. High-density oligonucleotide arrays were used to probe the genome content of the yeast Saccharomyces cerevisiae. We show that these arrays, containing oligonucleotides complementary to the sequenced strain of S. cerevisiae, can be used to identify open reading frames that are missing or present in higher or lower copy number in related isolates of S. cerevisiae. We apply this method to the characterization of the genome of a strain derived from a clinical isolate of S. cerevisiae. Our results show that the telomeres are the regions with the most variability between the two strains.

Status: Published Type: Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S. PubMed ID: 10466139

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Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
ARN2 ASP3-1 ASP3-2 ASP3-3 ASP3-4 ATS1 AYT1 BDS1 COS6 COS7
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Comparative genomic hybridization yg ball
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Topics Genes linked to topics (#11 - 20 )
COS8 FLO1 FMP32 HXT9 IMA1 IMA5 MAL11 MAL13 MST27 MST28
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Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#21 - 30 )
PDR5 PEX22 PRM8 PRM9 REE1 UIP3 YAR028W YAR029W YAR030C YAR053W
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Topics Genes linked to topics (#31 - 40 )
YAR060C YAR061W YCP4 YER186C YER188W YFL063W YFR057W YGL052W YGR290W YHL008C
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Topics Genes linked to topics (#41 - 50 )
YHL045W YHR054C YHR139C-A YIL080W YIL082W YIL082W-A YIR042C YIR043C YJL113W YJL114W
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Topics Genes linked to topics (#51 - 58 )
YJL218W YLR156W YLR159W YLR161W YLR162W YOL162W YOL163W YPS5
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Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Strains/Constructs blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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